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URL http://www.rockymountainbmt.com/news/Non-Hodgkin-lymphoma-NHL-could-be-treated-with-less-intensive-therapy-5101.html

Non-Hodgkin lymphoma (NHL) could be treated with less intensive therapy

10-04-2006

"Stage III NHL was divided into lower-risk (LR) or high-risk (HR) groups. Results of treatment were retrospectively reviewed for patients between 1993 through 2000," scientists in Saudi Arabia reported.

"An intensive multiagent protocol was used for IIIHR, and a CHOP-based, milder treatment for IIILR. Most LR therapy was outpatient, while treatment for HR patients was primarily inpatient. Five year EFS and OS for HR (n=29) and LR (n=23) groups was 86.2% and 95.6% (p=.26), and 93.1% and 100%, respectively (p=.4). LR had less toxicity," explained A.F. Belgaumi and colleagues, King Faisal Specialist Hospital & Research Center.

The researchers concluded, "While these results need prospective confirmation, the data shows that less intensive therapy of a LR group of stage III NHL may not impact negatively on outcome."

Belgaumi and colleagues published their study in Pediatric Blood & Cancer (Treatment of a clinically determined lower-risk stage III non-lymphoblastic non-Hodgkin lymphoma with less intensive therapy does not impact negatively on outcome. Pediatr Blood Cancer, 2006;46(3):367-371).

For additional information, contact A.F. Belgaumi, King Faisal Specialist Hospital & Research Center, Dept. Pediatrics Hematology Oncology, Sect Leukemia Lymphoma, POB 3354, MBC 53, Riyadh 11211, Saudi Arabia.

Keywords: Riyadh, Saudi Arabia, Chemotherapy, Low Risk, Non Hodgkin Lymphoma, Oncology, Pediatric, Staging, Treatment Intensity, Cancer Therapy.

This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2006, Clinical Oncology Week via NewsRx.com.